Peter Carlson, PhD, Awarded ICTR Pilot Grant with Paul Sondel, MD, PhD

Peter Carlson
Peter Carlson, PhD

Congratulations to Peter Carlson, PhD, graduate research assistant, along with mentor Paul Sondel, MD, PhD, professor, Hematology, Oncology and Bone Marrow Transplant, on the funding of their project, “Systemic pharmacokinetics of intratumorally injected hu14.18-IL2.” This one-year MSTP pilot grant in the amount of $7,800 was funded by the University of Wisconsin Institute for Clinical and Translational Research (ICTR). The primary aim is to develop an alternate assay for quantifying hu14.18-IL2 immunocytokine. The current assay uses large volumes of the 1A7 antibody, is limited in its throughput capacity, and takes several days to run. Success in this project will improve the understanding of the relation between intratumoral dose and systemic immunocytokine pharmacokinetics in both murine and clinical settings, which is critical in understanding systemic effects of local in situ vaccine approaches.