Bruce Klein, MD, Receives 5 Year Renewal Grant From NIH-NIAID

Congratulations to Bruce Klein, MD, on his recent R01 award of over $2.5 million from the National Institutes of Health - National Institute of Allergy and Infectious Diseases (NIH-NIAID). His 5-year renewal, "Molecular pathogenesis of Blastomycosis," provides funding for Years 20-24 of this project, in which the team will dissect the role and action of a yeast fungal product that inactivates innate immunity, enabling progressive infection. This work will yield insight into the microbial mechanism that underlies intense immune disturbances linked with a progressive systemic mycosis, while emphasizing action on GM-CSF and CCR2+ inflammatory monocytes, and the disabling consequences for innate immunity.