Matthew Harer receives NIH R01 award to study kidney hypoxia in neonates

The Eunice Kennedy Shriver National Institute of Child Health and Human Development awarded Matthew Harer, MD, associate professor in the Division of Neonatology and Newborn Nursery, his first National Institutes of Health R01 grant. He will be joined by Ryan McAdams, MD, professor, Division of Neonatology and Newborn Nursery, and Sin Yin Lim, PharmD, MS, assistant professor in the School of Pharmacy’s Division of Pharmacy Practice and Translational Research, as co-investigators on the project, “Optimizing Caffeine Therapy for Hypoxia in Preterm Neonates: A Randomized Trial Assessing Efficacy, Acute Kidney and Brain Injury, Safety, and Pharmacokinetics.” This project focuses on investigating the immediate and short-term kidney and brain outcomes if an additional IV caffeine citrate bolus is given versus placebo to premature neonates born less than 30 weeks gestation with kidney hypoxia measured by near infrared spectroscopy. The grant was awarded for $2,221,707 over the next five years, starting in September 2025 and ending in May 2030.