Margo Hoover-Reagan, MD, Receives ICTR Voucher Award to Study Prevention of Mucositis in Bone Marrow Transplant

Margo Hoover-Reagan, MD, was recently awarded a $5,000 voucher from the UW Institute for Clinical and Translational Research (ICTR), for her project entitled, “Topical Phenylephrine to Prevent Mucositis in Bone Marrow Transplant.” This funding mechanism is designed to rapidly advance the translation of discovery into therapy. Her study represents the first clinical trial step in the development of a novel therapeutic for prevention of oral mucositis, a common short-term complication of stem cell transplantation, which causes significant distress, expense, and morbidity. This study will support pharmacokinetic studies on serum of 5 patients to establish systemic absorption of phenylephrine, in the hopes of establishing a safe and effective mucositis prevention strategy, which would lead to immense benefits in patient morbidity including decreased use of pain medication and increased ability to take oral nutrition.