Angela Greenman, PhD, scientist I, Division of Cardiology, received a K99 award in the amount of $229,700 from National Heart, Lung, and Blood Institute. Greenman’s mentor for this project is J. Carter Ralphe, MD, professor in the same division. The project, “The role of myosin binding protein-C S-glutathionylation and phosphorylation on diastolic dysfunction in the diabetic heart,” aims to uncover new molecular mechanisms that link the S-glutathionylation and phosphorylation of cardiac myosin binding protein-C to better understand the role of sarcomere proteins in modulating relaxation of the diabetic heart. Prolongation of the heart’s relaxation phase is a hallmark of diabetic heart disease and a major public health concern given the high incidence of type II diabetes mellitus. Sarcomere proteins help to regulate relaxation parameters of the heart, and their modification might serve as a new target to treat diastolic dysfunction in the diabetic heart. The two-year K99 phase of the project began in September 2026. Pending the initial outcome, a three-year R00 phase will follow.