Drs. Otto and Bednarz Receive NIH Award to Study CLR1404

Congratulations to Mario Otto, MD, PhD, Principal Investigator, and co-PI, Bryan Bednarz, PhD, of the UW Department of Medical Physics, who were recently awarded a 2-year, R21 grant from the National Institutes of Health, National Cancer Institute (NIH/NCI), for their project entitled, "A cancer-targeted phospholipid ether analog for molecular radiotherapy of pediatric solid tumors."

This funding, in the amount of $366,053 will be used to investigate the highly tumor selective phospholipid ether analog CLR1404 as scaffold for delivery of radioiodine isotopes for molecular radiotherapy and personalized dosimetry in pre-clinical rodent models of pediatric solid cancers. The project has a strong potential to increase the dismal survival rate of children with these particularly deadly tumors.