Representative Publications

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Fagbuyi DB, Venkataraman S, Ralphe JC, Zuckerbraun NS, Pitetti RD, Lin Y, Jeong K, Saladino RA, Manole MD. Diastolic Hypotension, Troponin Elevation, and Electrocardiographic Changes Associated With the Management of Moderate to Severe Asthma in Children. Academic emergency medicine: official journal of the Society for Academic Emergency Medicine. 2016; 23(7):816-22. PubMed PMID: 27129445

Raval KK, Tao R, White BE, De Lange WJ, Koonce CH, Yu J, Kishnani PS, Thomson JA, Mosher DF, Ralphe JC, Kamp TJ. Pompe disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes. The Journal of biological chemistry. 2015; 290(5):3121-36. PubMed PMID: 25488666, PMCID: PMC4317045

Moss RL, Fitzsimons DP, Ralphe JC. Cardiac MyBP-C regulates the rate and force of contraction in mammalian myocardium. Circulation research. 2015; 116(1):183-92. NIHMSID: NIHMS646229 PubMed PMID: 25552695, PMCID: PMC4283578

De Lange WJ, Grimes AC, Hegge LF, Spring AM, Brost TM, Ralphe JC. E258K HCM-causing mutation in cardiac MyBP-C reduces contractile force and accelerates twitch kinetics by disrupting the cMyBP-C and myosin S2 interaction. The Journal of general physiology. 2013; 142(3):241-55. PubMed PMID: 23980194, PMCID: PMC3753599

Ralphe JC, de Lange WJ. 3D engineered cardiac tissue models of human heart disease: learning more from our mice. Trends in cardiovascular medicine. 2013; 23(2):27-32. PubMed PMID: 23295081, PMCID: PMC4066654

Egan KR, Ralphe JC, Weinhaus L, Maginot KR. Just sinus bradycardia or something more serious? Case reports in pediatrics. 2013; 2013:736164. PubMed PMID: 23476865, PMCID: PMC3582081

de Lange WJ, Grimes AC, Hegge LF, Ralphe JC. Ablation of cardiac myosin-binding protein-C accelerates contractile kinetics in engineered cardiac tissue. The Journal of general physiology. 2013; 141(1):73-84. PubMed PMID: 23277475, PMCID: PMC3536521