Representative Publications

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Smelter DF, De Lange WJ, Cai W, Ge Y, Ralphe JC. The HCM-linked W792R mutation in cardiac myosin binding protein-C reduces C6 FnIII domain stability. American journal of physiology. Heart and circulatory physiology. 2018; PubMed PMID: 29451820

Barton GP, de Lange WJ, Ralphe JC, Aiken J, Diffee G. Linking metabolic and contractile dysfunction in aged cardiac myocytes. Physiological reports. 2017; 5(20). PubMed PMID: 29084842, PMCID: PMC5661240

Kriegel AJ, Gartz M, Afzal MZ, de Lange WJ, Ralphe JC, Strande JL. Molecular Approaches in HFpEF: MicroRNAs and iPSC-Derived Cardiomyocytes. Journal of cardiovascular translational research. 2017; 10(3):295-304. PubMed PMID: 28032312, PMCID: PMC5937699

Farrell ET, Grimes AC, de Lange WJ, Armstrong AE, Ralphe JC. Increased Postnatal Cardiac Hyperplasia Precedes Cardiomyocyte Hypertrophy in a Model of Hypertrophic Cardiomyopathy. Frontiers in physiology. 2017; 8:414. PubMed PMID: 28659827, PMCID: PMC5470088

Fagbuyi DB, Venkataraman S, Ralphe JC, Zuckerbraun NS, Pitetti RD, Lin Y, Jeong K, Saladino RA, Manole MD. Diastolic Hypotension, Troponin Elevation, and Electrocardiographic Changes Associated With the Management of Moderate to Severe Asthma in Children. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 2016; 23(7):816-22. PubMed PMID: 27129445

Raval KK, Tao R, White BE, De Lange WJ, Koonce CH, Yu J, Kishnani PS, Thomson JA, Mosher DF, Ralphe JC, Kamp TJ. Pompe disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes. The Journal of biological chemistry. 2015; 290(5):3121-36. PubMed PMID: 25488666, PMCID: PMC4317045

Moss RL, Fitzsimons DP, Ralphe JC. Cardiac MyBP-C regulates the rate and force of contraction in mammalian myocardium. Circulation research. 2015; 116(1):183-92. PubMed PMID: 25552695, PMCID: PMC4283578