Division Highlights - Hematology, Oncology & Bone Marrow Transplant

The Division of Hematology, Oncology and Bone Marrow Transplant provides state-of-the-art integrated therapies, including stem cell transplant, aimed at curing malignancies and treating hematological disorders in children.

Research interests include ways to recognize and destroy cancer cells using immunologic, cellular and molecular biologic pathways, bone marrow transplantation as immunotherapy, cancer survivorship, neuro-oncology and palliative care.

2015 Highlights

  • Christian Capitini, MD, received a Vilas Faculty Early Career Investigator Award from the UW Provost Office. This award provides $50,000 in flexible research funds for his laboratory.

    Dr. Capitini also received two grants to support summer research in his lab: a Hematology Opportunities for the Next Generation of Research Scientists (HONORS) award from the American Society of Hematology, and a St. Baldrick's Summer Fellowship (awarded jointly with Paul Sondel, MD, PhD).
  • Thanks to a generous gift from Cynthia Crawford and the Morgridge match, Kenneth DeSantes, MD, was awarded the Crawford Professorship in Pediatric Oncology in 2015.
  • Mario Otto, MD, PhD, received a $250,000 Hyundai Scholar Hope Grant from Hyundai Hope on Wheels to produce pre-clinical data on a new small-molecule drug in combination with immunotherapy for solid tumor cancers that are particularly hard to treat.

    Dr. Otto and co-PI Bryan Bednarz, PhD, also received a two-year, $366,053 grant from the National Institutes of Health, National Cancer Institute (NIH/NCI) for their project, "A cancer-targeted phospholipid ether analog for molecular radiotherapy of pediatric solid tumors."
  • Diane Puccetti, MD, and co-PI Hrissanthi Ikonomidou, MD, PhD, (Neurology) received a one-year, $49,990 Basic and Clinical Pilot award from the UW Institute for Clinical and Translational Research (ICTR) for their proposal, "Methods to Study Chemotherapy-Related Neurotoxicity in Children."
  • Paul Sondel, MD, PhD, received a seven-year, $6 million R35 Outstanding Investigator Award (OIA) from the National Institutes of Health/National Cancer Institute (NIH-NCI) for his project, "Enhancing Antibody-directed Innate Immunity to Improve Cancer Outcome." This award will enable Dr. Sondel and co-investigators to collaborate on important research initiatives dedicated to the mutual goal of finding better treatments, via immune mechanisms, for cancer.

    In addition, Dr. Sondel received a one-year, $50,000 Novel Methods Pilot award from the UW Institute for Clinical and Translational Research (ICTR); a one-year, $105,773 research grant from St. Baldrick's Foundation; and a two-year, $250,000 Innovation Grant award from Alex's Lemonade Stand Foundation.

    Finally, Dr. Sondel was honored with the 2015 UW School of Medicine and Public Health Dean's Award for Excellence in Medical Student Research Mentorship. The award recognizes his longstanding involvement in student research programs and the research achievements of his medical student mentees.
  • Monica Gressett, an undergraduate student mentored by Paul Sondel, MD, PhD, and Amal Javaid, an undergraduate student mentored by Paul Sondel, MD, PhD, and Jacquelyn Hank, PhD, received 2015-2016 Wisconsin Hilldale Undergraduate/Faculty Research Fellowships for their projects, "The Effect of Radiation on Tumor Cell Susceptibility to Immune Response" and “Analysis of Anti-GD2 Monoclonal Antibody hu.14.18K322A Administered in Conjunction with NK Cells in the GD2NK Pediatric Neuroblastoma Trial.”
  • The Midwest Athletes Against Childhood Cancer (MACC) Fund is funding eight separate $100,000 grants by researchers in the Departments of Pediatrics and Human Oncology over the next two years. The grants will support research projects by Christian Capitini, MD; Kenneth DeSantes, MD; Jacquelyn Hank, PhD; Mario Otto, MD, PhD; Alexander Rakhmilevich, MD, PhD; and Paul Sondel, MD, PhD.
  • In 2015, U.S. News and World Report ranked American Family Children’s Hospital (AFCH) among the top 50 children’s hospitals for pediatric oncology.

 

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