The Division of Endocrinology and Diabetes provides state-of-the-art medical care through six multidisciplinary clinics: Diabetes, Endocrinology, Polycystic Ovarian syndrome, Turner syndrome, Pediatric and Adolescent Transgender Health, and Pediatric Fitness Clinics
Our research aims to improve the health and quality of life of children with diabetes and endocrine disorders, to understand the development and health effects of adipose tissue from infancy through adolescence, and to prevent childhood obesity and its consequences.
- Brittany Allen, MD, and Jennifer Rehm, MD, received a two-year, $80,000 Ira and Ineva Reilly Baldwin Wisconsin Idea Endowment grant entitled, "An Integrated PATH for Transgender Youth." This project aims to make the services and resources at the American Family Children’s Hospital Pediatric and Adolescent Transgender Health (PATH) clinic available to youth and advocates statewide, and will create a partnership with community advocates to support the whole transgender child and their family through integration of mental health, legal, educational, and advocacy services.
- Jennifer Rehm, MD, received a UW Health Patient Experience Champion Award for having achieved the highest level of exemplary patient/provider communication as recognized by her patients.
- Ei Terasawa, PhD, was recently awarded a one-year, $50,000 UW Institute for Clinical and Translational Research (ICTR) Basic and Clinical Translational Research Pilot award for her grant, "Generation of GnRH neurons from stem cells". This project will explore methods for generating gonadotropin-releasing hormone (GnRH) neurons from embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) derived from humans.
- Endocrinology and diabetes fellows Tasa Seibert, MD, Allison Pollock, MD, and Robert Strait, MD, received Pediatric Endocrine Society (PES) Travel Awards in 2015. Each received $750 to support their travel costs to the PES Annual Meeting in San Diego, California, in April 2015.
Dr. Strait also received a one-year, $5,000 Endocrine Fellows Foundation Research Grant for his project, "HPA axis activation by psychological stress as an independent risk factor for metabolic syndrome components in children.”
- In 2015, U.S. News and World Report ranked American Family Children’s Hospital (AFCH) among the top 50 children’s hospitals for pediatric endocrinology.
Professor and Division Chief
Associate Professor (CHS)
Allen DB, Backeljauw P, Bidlingmaier M, Biller BM, Boguszewski M, Burman P, Butler G, Chihara K, Christiansen J, Cianfarani S, Clayton P, Clemmons D, Cohen P, Darendeliler F, Deal C, Dunger D, Erfurth EM, Fuqua JS, Grimberg A, Haymond M, Higham C, Ho K, Hoffman AR, Hokken-Koelega A, Johannsson G, Juul A, Kopchick J, Lee P, Pollak M, Radovick S, Robison L, Rosenfeld R, Ross RJ, Savendahl L, Saenger P, Toft Sorensen H, Stochholm K, Strasburger C, Swerdlow A, Thorner M. GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults. Eur J Endocrinol. 2015 Feb;174(2):P1-9. Epub 2015 Nov 12. PubMed PMID: 26563978.
Allen DB. Inhaled corticosteroids and growth: still an issue after all these years. J Pediatr. 2015 Feb;166(2):463-9. Epub 2014 Nov 12. PubMed PMID: 25631291.
Ansari IU, Longacre MJ, Paulusma CC, Stoker SW, Kendrick MA, MacDonald MJ. Characterization of P4 ATPase phospholipid translocases (Flippases) in human and rat pancreatic beta cells: their gene silencing inhibits insulin secretion. J Biol Chem. 2015 Sep 18;290(38):23110-23. Epub 2015 Aug 3. PubMed PMID: 26240149.
Davies P, Connor E, MacKenzie J, Jamieson MA. Spontaneous recovery of ovarian function in an adolescent with galactosemia and apparent premature ovarian insufficiency. J Pediatr Adolesc Gynecol. 2015 Aug;28(4):e101-3. Epub 2014 Sep 16. PubMed PMID: 26024933. **
Flood TL, Zhao YQ, Tomayko EJ, Tandias A, Carrel AL, Hanrahan LP. Electronic health records and community health surveillance of childhood obesity. Am J Prev Med. 2015 Feb;48(2):234-40. PubMed PMID: 25599907.
Kapadia CR, Nebesio TD, Myers SE, Willi S, Miller BS, Allen DB, Jacobson-Dickman E; Drugs and Therapeutics Committee of the Pediatric Endocrine Society. Endocrine effects of inhaled corticosteroids in children. JAMA Pediatr. 2015 Dec 21:1-9. [Epub ahead of print] PubMed PMID: 26720105. *
Kenealy BP, Keen KL, Garcia JP, Richter DJ, Terasawa E. Prolonged infusion of estradiol benzoate into the stalk median eminence stimulates release of GnRH and kisspeptin in ovariectomized female rhesus macaques. Endocrinology. 2015 May;156(5):1804-14. Epub 2015 Mar 3. PubMed PMID: 25734362.
Kurian JR, Keen KL, Kenealy BP, Garcia JP, Hedman CJ, Terasawa E. Acute influences of bisphenol A exposure on hypothalamic release of gonadotropin-releasing hormone and kisspeptin in female rhesus monkeys. Endocrinology. 2015 Jul;156(7):2563-70. Epub 2015 Apr 8. PubMed PMID: 25853665.
MacDonald MJ, Ade L, Ntambi JM, Ansari IU, Stoker SW. Characterization of phospholipids in insulin secretory granules and mitochondria in pancreatic beta cells and their changes with glucose stimulation. J Biol Chem. 2015 Apr 24;290(17):11075-92. Epub 2015 Mar 11. PubMed PMID: 25762724.
Motosugi U, Hernando D, Bannas P, Holmes JH, Wang K, Shimakawa A, Iwadate Y, Taviani V, Rehm JL, Reeder SB. Quantification of liver fat with respiratory-gated quantitative chemical shift encoded MRI. J Magn Reson Imaging. 2015 Nov;42(5):1241-8. Epub 2015 Apr 1. PubMed PMID: 25828696.
Pollock AJ, Fost N, Allen DB. Growth attenuation therapy: practice and perspectives of paediatric endocrinologists. Arch Dis Child. 2015 Dec;100(12):1185. Epub 2015 Jul 22. PubMed PMID: 26203123.
Rehm JL, Wolfgram PM, Hernando D, Eickhoff JC, Allen DB, Reeder SB. Proton density fat-fraction is an accurate biomarker of hepatic steatosis in adolescent girls and young women. Eur Radiol. 2015 Oct;25(10):2921-30. Epub 2015 Apr 28. PubMed PMID: 25916386.
Watson AM, Eickhoff J, Nemeth BA, Carrel AL. In nonobese children, fitness and BMI are independent predictors of fasting insulin. Pediatr Exerc Sci. 2015 May;27(2):203-7. Epub 2015 Apr 15. PubMed PMID: 25875854.
Wolfgram PM, Allen DB. Factors influencing growth effects of inhaled corticosteroids in children. J Allergy Clin Immunol. 2015 Dec;136(6):1711-1712.e2. Review. PubMed PMID: 26654199.
Wolfgram PM, Connor EL, Rehm JL, Eickhoff JC, Zha W, Reeder SB, Allen DB. In nonobese girls, waist circumference as a predictor of insulin resistance is comparable to MRI fat measures and superior to BMI. Horm Res Paediatr. 2015;84(4):258-65. doi: 10.1159/000439130. Epub 2015 Sep 10. PubMed PMID: 26352642.
*ePub only; no print citation available when report was compiled** Publication had previously appeared in 2014 report as an ePub
Our faculty were principal investigators and/or co-investigators on the following grants during calendar year 2015.
|Allen, David B (PI)||Lilly (Eli) and Company||Fellowship Support (A. Pollock)|
|Allen, David B (PI)||Covance, Inc.||ANSWER Program Registry|
|Allen, David B (PI) with
Carrel, Aaron L (associate director)
|DHHS, PHS, National Institutes of Health||Childhood Diabetes Clinical & Molecular Research Training Program (T32)|
|Allen, David B (PI)||Pediatric Endocrine Society||PES Travel Grant (T. Seibert)|
|Allen, David B (PI)||Pediatric Endocrine Society||PES Travel Grant (A. Pollock)|
|Allen, David B (PI)||Pediatric Endocrine Society||PES Travel Grant (R. Strait)|
|Allen, David B (PI)||Endocrine Fellows Foundation||HPA Axis Activation by Psychological Stress as an Independent Risk Factor for Metabolic Syndrome Components in Children (R. Strait)|
|Allen, David B (co-I) with
Gern, James and
Busse, William (co-MPIs);
Jackson, Daniel (co-PI);
Bochkov, Yuri (Senior Scientist)
|DHHS, PHS, National Institutes of Health||Inner City Asthma Consortium 3 (ICAC3)|
|Bekx, M. Tracy (PI)||Wisconsin Dept of Health Services||Transition Pediatric Diabetes|
|Carrel, Aaron L (PI)||Genentech, Inc.||A Systematic Initiative to Evaluate the Effect of Adiposity and Fitness on Growth in a Statewide Cohort of Children|
|Carrel, Aaron L (co-I) with
Petty, Elizabeth (PI)
|Wisconsin Partnership Program||Engaging Clinicians in Online Social Learning to Close Knowledge Gaps in Community Health: Pilot Focus on Obesity and Mental Health Care|
|Carrel, Aaron L (co-I) with
Adams, Alexandra (PI)
|Wisconsin Partnership Program||Wisconsin Obesity Prevention Initiative|
|Carrel, Aaron L (academic partner with
Oneida County Health Department)
|Wisconsin Partnership Program||Northwoods LEAN (Linking Education, Activity and Nutrition): Pathways to Health|
|Carrel, Aaron L (co-I with
|Wisconsin Partnership Program||Growing Farm to School: Cultivating Childhood Wellness Through Gardening|
|MacDonald, Michael J (PI)||Mahidol University||Support for Lab Expenses|
|Rehm, Jennifer L (PI)||Thrasher Research Fund||Early Intervention and Prevention of Pediatric Non-Alcoholic Fatty Liver Disease|
|Rehm, Jennifer L (PI)||DHHS, PHS, National Institutes of Health||BIRCWH|
|Rehm, Jennifer L (co-project leader) with
Allen, Brittany (co-project leader)
|Reilly Baldwin Wisconsin Idea||An Integrated Path for Transgender Youth|
|Terasawa-Grilley, Ei (PI)||Wisconsin Alumni Research Foundation||Role of Neuroestradiol in Control of Gonadotropin-Releasing Hormone (GnRH) Release|
|Terasawa-Grilley, Ei (PI)||Wisconsin Alumni Research Foundation||FY15 Travel Grant|
|Terasawa-Grilley, Ei (PI)||DHHS, PHS, National Institutes of Health||Role of Neuroestrogens in Control of GnRH Release|
|Terasawa-Grilley, Ei (PI)||Massachusetts General Hospital||Kisspeptin and Neurokinin B: From Physiology in the Monkey to Pathophysiology in the Human|
|Terasawa-Grilley, Ei (PI)||DHHS, PHS, National Institutes of Health||Generation of GnRH Neurons from Stem Cells (ICTR Pilot)|