Representative Publications

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Soares L, Seroogy CM, Skrenta H, Anandasabapathy N, Lovelace P, Chung CD, Engleman E, Fathman CG (2004) Two isoforms of otubain 1 regulate T cell anergy via GRAIL. Nature Immunology, 5(1): 45-54.

Seroogy CM, Soares L, Ranheim EA, Su L, Holness C, Bloom D, Fathman CG (2004) GRAIL, an E3 ubiquitin ligase, is necessary for the induction of anergy in CD4+ T cells. Journal of Immunology, 173(1): 79-85.

Seroogy CM and Gern JE (2005) The Role of T Regulatory Cells in Asthma. Journal of Allergy and Clinical Immunology, 116(5): 996-9.

MacKenzie DA, Schartner J, Lin J, Timmel A, Jennens-Clough M, Fathman CG, Seroogy CM (2007) GRAIL is Upregulated in CD4+CD25+ T Regulatory Cells and is Sufficient for Conversion of T Cells to a Regulatory Phenotype. Journal of Biological Chemistry, 282(13): 9696-9702.

Schartner J, Fathman CG, Seroogy CM (2007) Preservation of Self: An Overview of E3 Ubiquitin Ligases and T Cell Tolerance. Seminars in Immunology, 19 (3): 188-96.

Jartti T, Burmeister K, Seroogy CM, Jennens-Clough ML, Tisler C, Pleiss L, Evans M, Vrtis R, Wallace P, Ruiz B, Gangnon R, Lemanske RF, and Gern JE (2007) Association between CD4+CD25high T Cells and Atopy in Children. Journal of Allergy and Clinical Immunology, 120 (1): 177-83.

Dahlberg, PE, Schartner, JM, Timmel, A, Seroogy, CM (2007) Daily Subcutaneous Injections of Peptide Induce CD4+ CD25+ T Regulatory Cells. Clinical and Experimental Immunology, 149 (2): 226-34.

Schartner JM, Singh AM, Dahlberg PE, Nettenstrom L, Seroogy CM (2009) Superantigen Exposure In Vivo Leads to Highly Suppressive CD4+CD25+ and CD4+CD25- T Cells with Anergic and Suppressive Genetic Signatures. Clinical and Experimental Immunology, 155(2): 348-56.

Schartner JM, William T. Simonson, Sarah A. Wernimont, Lauren M. Nettenstrom, Anna Huttenlocher, Seroogy, CM (2009) Gene Related to Anergy in Lymphocytes (GRAIL) Expression in CD4+ T Cells Impairs Actin Cytoskeletal Organization During T Cell: Antigen Presenting Cell Interactions. Journal of Biological Chemistry, Dec 11;284(50):34674-81, PMID: 19833735; PMCID: PMC2787330.

ingh AM, Evans MD, Gangnon R, Roberg KA, Tisler C, DaSilva D, Pappas T, Salazar L, Gern JE, Lemanske, RF and Seroogy CM (2010) Expression patterns of atopic eczema and respiratory illnesses in a high-risk birth cohort. Journal of Allergy and Clinical Immunology. Feb; 125(2): 492-493, PMID: 20159261; NIHMSID: NIHMS232583.