The National Institutes of Health have awarded a five year, $16 million grant to a group of researchers including Bruce Klein, MD, to find new sources of antibiotics to combat the rising number of deadly antibiotic-resistant infections. The UW-Madison team is studying natural products from animals, insects, plants and marine life, searching for novel antimicrobials to combat two groups of relevant microbes: fungi associated with infections in immunocompromised patients like cancer and transplant patients, and bacteria responsible for the majority of U.S. hospital infections.