The Division of Pediatric Pulmonology and Sleep Medicine provides interdisciplinary family-centered care for children with respiratory disorders, including asthma, cystic fibrosis, sleep disorders, neuromuscular disorders, and chronic lung disease.
The division continues to build upon leading-edge clinical research into the early diagnosis and epidemiology of cystic fibrosis with new investigations into the disease’s microbiome. Additional clinical research focuses on environment-disease interactions in asthma, pulmonary management of children with neuromuscular disorders, education and effect of sleep disorders in children. The division also has an active translational research program that is investigating the role of stem and progenitor cells in newborn lung disease.
- Vivek Balasubramaniam, MD, received the Society for Pediatric Research’s (SPR) Thomas Hazinski Distinguished Service Award for his exceptional service to the SPR and his deep commitment to advocacy initiatives and furthering child health and child health research.
Dr. Balasubramaniam will also serve as a co-investigator/subaward principal investigator on a four-year R01 grant from the National Institutes of Health/National Heart, Lung, and Blood Institute for the project, “Specific Lysis for Large-Volume, High-Purity Endothelial Progenitor Cell Isolates” (principal investigator: Bradley Berron, PhD, the University of Kentucky).
- The research team led by Principal Investigator HuiChuan Lai, PhD (Nutritional Sciences), and Co-Investigators Philip Farrell, MD, PhD, and Michael Rock, MD, received a five-year, $3,435,587 R01 grant from the National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases for the project, "Early Childhood Diet, Growth, Gut Microbiome and Lung Health in Cystic Fibrosis."
- Michael Rock, MD, received a two-year, $177,755 Additional Research Coordinator Award from the Cystic Fibrosis Foundation Therapeutics, Inc. (CFFT).
- Mary Schroth, MD, received a five-year, $1,700,000 Pediatric Pulmonary Center (PPC) training grant competitive renewal from the Department of Health and Human Services (DHHS).
- In 2016, U.S. News and World Report ranked American Family Children’s Hospital (AFCH) among the top 50 children’s hospitals for pediatric pulmonology.
Associate Professor (CHS)
and Division Chief
Associate Professor (CHS)
Assistant Professor (CHS)
Baker MW, Atkins AE, Cordovado SK, Hendrix M, Earley MC, Farrell PM. Improving newborn screening for cystic fibrosis using next-generation sequencing technology: a technical feasibility study. Genet Med. 2016 Mar;18(3):231-8. doi: 10.1038/gim.2014.209. Epub 2015 Feb 12. PubMed PMID: 25674778; PubMed Central PMCID: PMC4802962. **
Farrell PM, Sommerburg O. Toward quality improvement in cystic fibrosis newborn screening: Progress and continuing challenges. J Cyst Fibros. 2016 May;15(3):267-9. doi: 10.1016/j.jcf.2016.04.008. Epub 2016 May 10. PubMed PMID: 27172835.
Lenhart RL, Youlo S, Schroth MK, Noonan KJ, McCarthy J, Mann D, Hetzel S, Sund SA, Halanski MA. Radiographic and respiratory effects of growing rods in children with spinal muscular atrophy. J Pediatr Orthop. 2016 Sep 15. [Epub ahead of print] PubMed PMID: 27636914. *
Levy H, Nugent M, Schneck K, Stachiw-Hietpas D, Laxova A, Lakser O, Rock M, Dahmer MK, Biller J, Nasr SZ, Baker M, McColley SA, Simpson P, Farrell PM. Refining the continuum of CFTR-associated disorders in the era of newborn screening. Clin Genet. 2016 May;89(5):539-49. doi: 10.1111/cge.12711. Epub 2016 Jan 20. PubMed PMID: 26671754.
Levy JF, Rosenberg MA, Farrell PM. Innovative assessment of inpatient and pulmonary drug costs for children with cystic fibrosis. Pediatr Pulmonol. 2016 Dec;51(12):1295-1303. doi: 10.1002/ppul.23554. PubMed PMID: 27740724.
Ramratnam SK, Visness CM, Jaffee KF Ms, Bloomberg GR, Kattan M, Sandel MT, Wood RA, Gern JE, Wright RJ. Relationships among maternal stress and depression, Type 2 responses, and recurrent wheezing at age 3 years in low income urban families. Am J Respir Crit Care Med. 2016 Sep 21. [Epub ahead of print] PubMed PMID: 27654103. *
Wong SL, Balasubramaniam V. A healthier future requires policy informed by lifespan science. Pediatr Res. 2016 Dec 7. doi: 10.1038/pr.2016.243. [Epub ahead of print] PubMed PMID: 27846198. *
Zhang Z, Lindstrom MJ, Farrell PM, Lai HJ; Wisconsin Cystic Fibrosis Neonatal Screening Group. Pubertal height growth and adult height in cystic fibrosis after newborn screening. Pediatrics. 2016 May;137(5). pii: e20152907. doi: 10.1542/peds.2015-2907. Epub 2016 Apr 5. PubMed PMID: 27244789; PubMed Central PMCID: PMC4845866.
*ePub only; no print citation available when report was compiled
** Publication had previously appeared in 2015 report as an ePub
Our faculty were principal investigators and/or co-investigators on the following grants during calendar year 2016.
|Balasubramaniam, Vivek (co-I) with McCulley, David (co-I) and Sun, Xin (PI)||DHHS, PHS, National Institutes of Health||Respiratory Deficiencies in Congenital Diaphragmatic Hernia|
|Farrell, Phillip M (co-I) with Lai, Huichan (PI)||Cystic Fibrosis Foundation Therapeutics||Feeding Infants Right...from the STart (FIRST) Study|
|Farrell, Phillip M (co-I) with Lai, Huichan (PI)||Cystic Fibrosis Foundation Therapeutics||Early Childhood Diet, Growth, Gut Microbiome and Lung Health in Cystic Fibrosis (R01 Bridge Support)|
|Farrell, Phillip M (co-I) with Lai, Huichan (PI) and Rock, Michael (co-I)||DHHS, PHS, National Institutes of Health||Early Childhood Diet, Growth, Gut Microbiome and Lung Health in Cystic Fibrosis|
|Farrell, Phillip M (co-PI) with Baker, Mei (co-PI) and Rock, Michael J (co-I)||Legacy of Angels Foundation||A Prospective Study of Newborn Screening for Cystic Fibrosis Using a Novel IRT/Next Generation Sequencing Method|
|Farrell, Phillip M (co-I) with Lai, Huichan (PI) and Rock, Michael (co-I)||DHHS, PHS, National Institutes of Health||Newborn Screening, Malnutrition and Lung Disease in Children with Cystic Fibrosis|
|Ramratnam, Sima K (co-I) with Jarjour, Nizar (PI)||DHHS, PHS, National Institutes of Health||Stability of Severe Asthma Phenotypes: Impact of Exacerbations (SARP III)|
|Ramratnam, Sima K (co-I) with Lemanske, Robert and Sorkness, Christine (co-MPIs); Jackson, Daniel J (co-I)||DHHS, PHS, National Institutes of Health||AsthmaNet|
|Rock, Michael J (PI)||Children's Hospital and Regional Medical||EPIC-002|
|Rock, Michael J (PI)||Seattle Children's Hospital||CFFC-OB-11|
|Rock, Michael J (PI)||Seattle Children's Hospital||AquADEKs-2-IP-12|
|Rock, Michael J (PI)||Registrat||VTPP|
|Rock, Michael J (PI)||Legacy of Angels||A Multi-Center Study of a New Method of Sweat Testing: the CF Quantum Sweat Test|
|Rock, Michael J (PI)||Seattle Children's Hospital||OPTIMIZing Treatment for Early Pseudomonas Aeruginosa Infection in Cystic Fibrosis: The OPTIMIZE Multicenter Randomized Trial|
|Rock, Michael J (PI)||Cystic Fibrosis Foundation||CF Center Grant|
|Rock, Michael J (PI)||Cystic Fibrosis Foundation Therapeutics||CFFT Therapeutic Development Network|
|Rock, Michael J (PI)||University of North Carolina-Chapel Hill||Variability in Sweat Testing Assays (VISTA)|
|Rock, Michael J (PI)||Cystic Fibrosis Foundation||Fundamentals LLC 2015-2016|
|Rock, Michael J (PI)||Vertex Pharmaceuticals Inc||VX14-809-109|
|Rock, Michael J (PI)||Wisconsin Dept of Health Services||Congenital Disorders|
|Rock, Michael J (PI)||Cystic Fibrosis Foundation Therapeutics||ARC (Additional Research Coordinator) Award|
|Rock, Michael J (PI)||Cystic Fibrosis Foundation||Barreda, Christina 2 year CFF Clinical Fellowship|
|Rock, Michael J (PI)||Vertex Pharmaceuticals Inc||Vertex VX15-809-110|
|Rock, Michael J (PI)||Vertex Pharmaceuticals Inc||Vertex VX14-661-108|
|Rock, Michael J (PI)||Vertex Pharmaceuticals Inc||Vertex VX15-770-124|
|Rock, Michael J (PI)||Seattle Children's Hospital||SHIP 001|
|Sanders, Don B (PI)||Gilead Sciences||Determinants of the Airway Microbiome in Infants with CF|
|Sanders, Don B (PI)||Cystic Fibrosis Foundation Therapeutics||Standardized Treatment Of Pulmonary Exacerbations II (STOP2)|
|Sanders, Don B (PI)||DHHS, PHS, National Institutes of Health||Determinants of the Microbiome in Young Children with Cystic Fibrosis|
|Schroth, Mary K (PI)||Muscular Dystrophy Association, Inc||MDA-Sponsored Clinic|
|Schroth, Mary K (PI) with Matthews Camilla B; Rock Michael J and Sanders DB (faculty)||DHHS, PHS, Health Resources and Services||Pediatric Pulmonary Center (PPC) Training Grant|