Division Highlights - Endocrinology & Diabetes

The Division of Endocrinology and Diabetes provides state-of-the-art medical care through four multidisciplinary clinics: diabetes, endocrinology, polycystic ovarian syndrome, and pediatric fitness.

Our research aims to improve the health and quality of life of children with diabetes and endocrine disorders and to prevent childhood obesity and its consequences.

2011 Highlights

  • David Allen, MD, served as president of the Pediatric Endocrine Society and was selected as chair of its 10th International Meeting in Pediatric Endocrinology, which will be held in 2017.
  • The J Biol Chem paper (“Differences between human and rodent pancreatic islets…,” listed below) authored by Michael MacDonald, MD, was the featured investigator research article in the 2011 Integrated Islet Distribution Program newsletter.
  • Fellows Vanessa Curtis, MD; Jennifer Rehm, MD; and Peter Wolfgram, MD, each received the  Pediatric Endocrine Society's (PES) Travel Award to support their travel costs to the PES Annual Meeting.
  • Fellow Jennifer Rehm, MD, received two fellowship research awards in 2011. The first was the Society for Pediatric Research’s Fellow Clinical Research Award, which was awarded for her abstract, “Fatty Liver Disease in Overweight Adolescent Girls Measured with Quantitative MRI and MR Spectroscopy.” The second award was a $50,000 Pediatric Endocrine Society Research Fellowship Award, which supports her final year of research training in preparation for a career in academic pediatric endocrinology.
  • Fellow Peter Wolfgram, MD, received a $15,000 Marilyn Fishman Grant for Diabetes Research from the Endocrine Fellows Foundation for his project, "The Role of Ethnicity and Race in Site Specific Fat Distribution, Inflammation and Insulin Resistance in Children." He also received a two-year, $100,000 fellowship award from the Genentech Center for Clinical Research in Endocrinology for his project, “Role of Ethnicity in Fat Distribution and Insulin Resistance.”

Faculty


Michael J. MacDonald, MD

Professor and Division Chief

David B. Allen, MD

Professor

M. Tracy Bekx, MD

Assistant Professor

Aaron L. Carrel, MD

Associate Professor

Ellen L. Connor, MD

Associate Professor

Ei Terasawa, PhD

Professor

   

Recent Publications

Allen DB. Chairman's summary: Roundtable discussion – Safety of growth hormone treatment. Horm Res Paediatr. 2011;76 Suppl 3:33. PMID: 21912158.

Allen DB. Clinical review: Lessons learned from the hGH era. J Clin Endocrinol Metab. 2011 Oct;96(10):3042-7. PMID: 21865374.

Allen DB. Safety of growth hormone treatment of children with idiopathic short stature: the US experience. Horm Res Paediatr. 2011;76 Suppl 3:45-7. PMID: 21912165.

Curtis VA, Allen DB. Boosting the late blooming male: Use of growth promoting agents in the athlete with constitutional delay of growth and puberty. Sports Health. 2011 Jan;3(1):32-40. PMID: 21691451.

Fahien LA, Macdonald MJ. The complex mechanism of glutamate dehydrogenase in insulin secretion. Diabetes. 2011 Oct;60(10):2450-4. PMID: 21948999.

Fuenzalida LC, Keen KL, Terasawa E. Colocalization of FM1-43, Bassoon, and GnRH-1: GnRH-1 release from cell bodies and their neuroprocesses. Endocrinology.  2011 Nov;152(11):4310-21. PMID: 21896672.

Guerriero KA, Keen KL, Millar RP, Terasawa E. Developmental changes in GnRH release in response to kisspeptin agonist and antagonist in female rhesus monkeys (macaca mulatta): Implication for the mechanism of puberty. Endocrinology. 2012 Feb;153(2):825-36. Epub 2011 Dec 13. PMID: 22166978.

Guilbert TW, Mauger DT, Allen DB, Zeiger RS, Lemanske RF Jr, Szefler SJ, Strunk RC, Bacharier LB, Covar R, Sorkness CA, Taussig LM, Martinez FD; Childhood Asthma Research and Education Network of the National Heart, Lung, and Blood Institute. Growth of preschool children at high risk for asthma 2 years after discontinuation of fluticasone. J Allergy Clin Immunol. 2011 Nov;128(5):956-63.e1-7. PMID: 21820163.

MacDonald MJ, Longacre MJ, Stoker SW, Kendrick M, Thonpho A, Brown LJ, Hasan NM, Jitrapakdee S, Fukao T, Hanson MS, Fernandez LA, Odorico J. Differences between human and rodent pancreatic islets: low pyruvate carboxylase, atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets. J Biol Chem. 2011 May 27;286(21):18383-96. PMID: 21454710.

Vivian EM, Carrel AL, Becker T. Identifying children at risk for type 2 diabetes in underserved communities. Diabetes Educ. 2011 Jul-Aug;37(4):519-27. PMID: 21617176.

Grant Support


Principal Investigator Funding Agency Title
Allen, David Covance Inc ANSWER Registry
Allen, David Genentech, Inc Role of Ethnicity - P. Wolfgram
Allen, David Pediatric Endocrine Society Curtis - PES Travel Grant
Allen, David Pediatric Endocrine Society Early Detection of Fatty Liver - J. Rehm
Allen, David Pediatric Endocrine Society Rehm - PES Travel Grant
Allen, David Pediatric Endocrine Society Wolfgram - PES Travel Grant
Allen, David Pfizer, Inc KABI International Growth Study
Carrel, Aaron UWF - Wisconsin Partnership Program - MERC Effects of Environmental Opportunities and Barriers to Physical Activity, Fitness and Health in Hispanic Children in Wisconsin
Conner, Ellen Endocrine Fellows Foundation Prevalence Hepatic Steatosis in Adolescents with Polycystic Ovary Syndrom - J. Rehm
Conner, Ellen Genentech, Inc Hepatic Steatosis in Adolescents with Polycystic Ovary Syndrome - J. Rehm
MacDonald, Michael DHHS, PHS, National Institutes of Health Childhood Diabetes Clinical & Molecular Research Training Program
MacDonald, Michael DHHS, PHS, National Institutes of Health Glucose/Secretagogue Metabolism in Pancreatic Islets

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