Division Highlights - Critical Care

The Division of Pediatric Critical Care Medicine delivers comprehensive, state-of-the-art care to critically ill children admitted to American Family Children’s Hospital.

Our scholarly endeavors include advocacy, medical education, clinical and basic science research, and global health.

2010 Highlights

  • Juan Boriosi, MD, was in the top 10 percent of enrollers in a Hospira-funded multicenter trial.
  • Tom Brazelton, MD, MPH, FAAP, was promoted to vice chair for quality improvement for the department. He was also elected to the executive committee of the board of directors for the Committee on Accreditation of EMS Training Programs.
  • Pelin Cengiz, MD, and Michael Wilhelm, MD, were elected to the Society for Pediatric Research.
  • Melissa Cercone, MD, became associate director of the department’s residency program.
  • Marlowe Eldridge, MD, was a Hartwell Foundation research award finalist, and became a co-PI on a National Heart, Lung, and Blood Institute contract on production assistance for cellular therapies.
  • Peter Ferrazzano, MD, received a renewal of his KL2 Scholar Award from the UW Institute for Clinical And Translational Research. The award supports his work on pediatric brain injury and neuroprotection.
  • Greg Hollman, MD, was chairman and course director of the 2010 International Pediatric Sedation Provider Course.

Faculty


Marlowe W. Eldridge, MD

Associate Professor and
Division Chief

Rahul Bhatia, MD

Assistant Professor

Juan P. Boriosi, MD

Assistant Professor

Tom Brazelton, MD, MPH

Associate Professor

Pelin Cengiz, MD

Assistant Professor

Melissa A. Cercone, MD

Assistant Professor

Peter A. Ferrazzano, MD

Assistant Professor

Scott A. Hagen, MD

Assistant Professor

Gregory A. Hollman, MD

Professor

Michael Wilhelm, MD

Assistant Professor

   

Recent Publications

Boriosi JP, Sapru A, Hanson JH, Asselin J, Gildengorin G, Newman V, Sabato K,  Flori HR. Efficacy and safety of lung recruitment in pediatric patients with acute lung injury. Pediatr Crit Care Med. 2010 Nov 4.

Cengiz P, Kleman N, Uluc K, Kendigelen P, Hagemann T, Akture E, Messing A, Ferrazzano P, Sun D. Inhibition of Na(+)/H(+) Exchanger Isoform 1 Is Neuroprotective in Neonatal Hypoxic Ischemic Brain Injury. Antioxid Redox Signal. 2010 Dec 4.

Kleman NW, Sun D, Cengiz P. Mechanisms underlying neonatal hypoxia ischemia. The Open Drug Discovery Journal. 2010; 2:129-137.

Liu Y, Kintner DB, Begum G, Algharabli J, Cengiz P, Shull GE, Liu XJ, Sun D. Endoplasmic reticulum Ca2+ signaling and mitochondrial Cyt c release in astrocytes following oxygen and glucose deprivation. J Neurochem. 2010 Sep 1;114(5):1436-46.

Amann M, Regan MS, Kobitary M, Eldridge MW, Boutellier U, Pegelow DF, Dempsey JA. Impact of pulmonary system limitations on locomotor muscle fatigue in patients with COPD. Am J Physiol Regul Integr Comp Physiol. 2010 Jul;299(1):R314-24.

Eldridge MW. Exercise-induced pulmonary edema: the debate continues. J Appl Physiol. 2010 Oct;109(4):1279-80.

Limberg JK, Eldridge MW, Proctor LT, Sebranek JJ, Schrage WG. Alpha-adrenergic control of blood flow during exercise: effect of sex and menstrual phase. J Appl Physiol. 2010 Nov;109(5):1360-8.

Hollman GA, Allen DB, Eickhoff JC, Carrel AL. Respiratory depression in young Prader Willi Syndrome patients following clonidine provocation for growth hormone secretion testing. Int J Pediatr Endocrinol. 2010;2010:103742.

Grant Support


Principal Investigator Funding Agency Title
Boriosi, Juan Hospira Pharmacuticals Hospira HOSDEX85-DEX805
Boriosi, Juan NIH/NHLBI Targeted Genomic Analysis of Coagulation Pathway in Acute Lung Injury
Boriosi, Juan Roche Oseltamivir IV: A Phase II trial in Pediatrics
Boriosi, Juan Isomark and UW ICTR Pilot Grant Isomark 13CO2/12CO2 Breath Analyzer
Cengiz, Pelin Department of Pediatrics R&D Grant Role of Na+/H+ Exchanger Isoform 1 (NHE1) in Neonatal Hypoxic Ischemic Encephalopathy
Eldridge, Marlowe NIH/NHLBI Comprehensive Characterization of Intrapulmonary Arteriovenous Pathways in Health
Eldridge, Marlowe NIH/NHLBI Production Assistance for Cellular Therapies
Eldridge, Marlowe NIH/NHLBI Respiratory Neurobiology Training Program
Eldridge, Marlowe American Heart Association Intrapulmonary Shunt Pathways in Pediatric Stroke
Eldridge, Marlowe NIH Aging and Microvascular Dysfunction in Human Skeletal Muscles
Ferrazzano, Peter NIH NCRR (ICTR KL2 Scholars Award) MRI Biomarkers in Pediatric Cerebral Ischemia and Neuroprotection
Ferrazzano, Peter NIH NINDS The Role of the Na+/H+ Exchanger in Cerebral Ischemia
Wilhelm, Michael NIH NCRR (ICTR KL2 Scholars Award) Regulation of Dendritic APP Translation by the JNK Pathway in Fragile X Syndrome

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