Division Highlights - Pulmonology & Cystic Fibrosis

2007 - 2008 Highlights

Mary Schroth, MD, participates in Phase I and II trials for treatment of spinal muscular atrophy

The Department of Health and Human Services-funded Pediatric Pulmonary Center is one of the two longest-funded programs in the nation

Theresa Guilbert, MD, receives a UW ICTR Type 1 research grant

Overview

The Division of Pediatric Pulmonology provides family-centered, community-based, culturally competent care for children with lung diseases.

Our team includes physicians, nurses, respiratory therapists, social workers, dieticians, pharmacists, psychologists, interdisciplinary students, and administrative support staff.

The division provides traditional and distance education to undergraduate and graduate students in nursing, nutrition, social work, respiratory care, pharmacy, and medicine. It also delivers postgraduate and in-service training programs in all disciplines.

The division conducts clinical, transitional and basic research in support of its ultimate goal: to improve the health of children with lung diseases.

Faculty

Division Chief: Michael J. Rock, MD, Professor Philip M. Farrell, MD, PhD, Professor

Michael J. Rock, MD

Residency: University of Oklahoma College of Medicine, Oklahoma City, Oklahoma

Fellowships: Pediatric Pulmonology, University of Wisconsin-Madison Medical School, Madison, WI

Board certification: Pediatrics, Pediatric Pulmonary

Clinical interests: cystic fibrosis

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Philip M. Farrell, MD, PhD

Residency: University of Wisconsin Children’s Hospital

Fellowships: Pediatric Pulmonology, National Institutes of Health, Bethesda, Maryland

Board certification: Pediatrics, Medicine, Neonatology/Perinatology

Clinical interests: cystic fibrosis, newborn screening and prevention of prematurity in African American infants

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Christopher G. Green, MD, Professor Theresa W. Guilbert, MD, Assistant Professor

Christopher G. Green, MD

Residency: University of Wisconsin-Madison Medical School

Fellowships: Pediatric Pulmonology, Case Western University, Cleveland, Ohio

Board certification: Pediatrics, Pediatric Pulmonary

Clinical interests: pulmonary diagnostic techniques, pulmonary physiology, flexible bronchoscopy, apnea and cystic fibrosis

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Theresa W. Guilbert, MD

Residency: University of Minnesota, Minneapolis, Minnesota

Fellowships: Pediatric Pulmonology, University of Colorado, Denver, Colorado

Board certification:Pediatrics, Pediatric Pulmonary

Clinical interests: early childhood wheezing, asthma and interstitial lung disease

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D. B. Sanders, MD, Assistant Professor Mary K. Schroth, MD, Associate Professor

D. B. Sanders, MD

Residency: Children’s Memorial Hospital, Chicago, IL

Fellowships: Pediatric Pulmonology, Seattle Children’s Hospital, Seattle, Washington

Board certification: Pediatrics, Pediatric Pulmonary

Clinical interests: cystic fibrosis, asthma and early childhood wheezing

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Mary K. Schroth, MD

Residency: University of Iowa Hospitals and Clinics, Iowa City, Iowa

Fellowships: Pediatric Pulmonology, University of Iowa Hospitals and Clinics, Iowa City, Iowa

Board certification: Pediatrics, Pediatric Pulmonary

Clinical interests: neuromuscular disease

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Recent Publications

Philip M. Farrell, MD, PhD

Rosenberg MA, Farrell PM. Predictive Modeling of costs for a chronic disease with acute high cost episodes. North American Actuarial J. 2008; 12: 1­18.

Farrell, PM. Is newborn screening for cystic fibrosis a basic human right? J Cyst Fibros. 2008 May;7(3):262-265. PubMed PMID: 18262856, PMCID: PMC2504861

Shafer MM, Siker M, Overdier JT, Ramsl PC, Teschler-Nicola M, Farrell PM. Enhanced methods for assessment of the trace element composition of Iron Age bone. Sci Total Environ. 2008 Aug 15;401(1-3): 144-161. PubMed PMID: 18486196

Farrell PM, Beryl J. Rosenstein BJ, White TW, Accurso FJ, Castellani C, Cutting GR, Durie PR, Vicki A. LeGrys VA, Massie J, Rock MJ,, Campbell PW, and participants in the CF Foundation Consensus Conference. Guidelines for diagnosis of cystic fibrosis in the era of newborn screening: Cystic Fibrosis Foundation consensus report. J Pediatr. 2008 Aug;153(2):S4-S14. PubMed PMID: 18639722, PMCID: PMC2810958

Farrell PM. The prevalence of cystic fibrosis in the European Union. J Cyst Fibros. 2008 Sept;7:450-3. PubMed PMID: 18442953


Theresa W. Guilbert, MD

Guilbert TW, Moss, M, Lemanske RF. P Asthma. In Middleton’s Allergy Principles and Practice Textbook 7th Edition, Lemankse RF Ed. Elsevier, Ltd, London, England, In Press 2008.

Tippets B, Guilbert TW. Asthma Management in Children. Accepted for publication Consultant for Pediatricians, August 2008.

Strunk RC, Bacharier LB, Phillips BR, Szefler SJ, Zeiger RS, Chinchilli VM, Martinez FD, Lemanske RF Jr, Taussig LM, Mauger DT, Morgan WJ, Sorkness CA, Paul IM, Guilbert T, Krawiec M, Covar R, Larsen G; CARE Network. Azithromycin or montelukast as inhaled corticosteroid-sparing agents in moderate-to-severe childhood asthma study. J Allergy Clin Immunol. 2008 Dec; 122(6):1138-1144.e4. Epub 2008 Oct 25. PubMed PMID: 18951618, PMCID: PMC2737448

Bacharier LB, Phillips BR, Zeiger RS, Szefler SJ, Martinez FD, Lemanske RF Jr, Sorkness CA, Bloomberg GR, Morgan WJ, Paul IM, Guilbert T, Krawiec M, Covar R, Larsen G, Mellon M, Moss MH, Chinchilli VM, Taussig LM, Strunk RC; CARE Network. Episodic use of an inhaled corticosteroid or leukotriene receptor antagonist in preschool children with moderate-to-severe intermittent wheezing. J Allergy Clin Immunol. 2008 Dec;122(6):1127-1135.e8. Epub 2008 Oct 30. PubMed PMID: 18973936, PMCID: PMC2753208


D.B. Sanders, MD, MS

D.B. Sanders, Margaret Rosenfeld, Nicole Mayer-Hamblett, David Stamey, and Gregory Redding. Reproducibility of Spirometry during Cystic Fibrosis Pulmonary Exacerbations. Accepted (pending minor revisions): Pediatric Pulmonology. 2008 May.

D.B. Sanders and Cynthia Labella. “Athletic Trainers’ Education, Experience, and Skills in Managing Asthma.” Submitted to: Journal of Athletic Training, March 2008.


Mary K. Schroth, MD

Durkin E, Schroth MK, Helin M, Shaaban A. Early laparoscopic fundoplication and gastrostomy in infants with Spinal Muscular Atrophy Type I. J Pediatr Surg. 2008 Nov; 43(11): 2031-7. PubMed PMID: 18970936

Grant Support

Philip M. Farrell, MD, PhD

  • Cystic Fibrosis Foundation FARREL06A0 (2006-2011)
    “Pulmonary Benefits of Cystic Fibrosis Neonatal Screening: Psychosocial Outcomes”
  • NIH 2RO1 DK 34108 (2007-2012)
    “Pulmonary Benefits of Cystic Fibrosis Neonatal Screening”
  • Cystic Fibrosis Foundation (2008-2011)
    “Transmission of S. aureus from Parents to CF Infants”

Michael J. Rock, MD

  • Children’s Hospital and Regional Medical Center (04/01/05-present)
    “EPIC-002: Longitudinal Assessment of Risk Factors For and Impact of Pseudomonasaeruginosa Acquisition and Early Anti-pseudomonal Treatment in Children with CF”
    Role: PI for University of Wisconsin site of multicenter study
  • Children’s Hospital and Regional Medical Center (06/01/05-present)
    “EPIC-001: Effectiveness and Safety of Intermittent Antimicrobial Therapy of the Treatment of New Onset Pseudomonas aeruginosa Airway Infection in Young Patients with Cystic Fibrosis”
    Role: PI for University of Wisconsin site of multicenter study
  • NIH (7/15/06-6/30/11)
    “Malnutrition and Lung Disease in Cystic Fibrosis”
    Role: Co-Investigator
  • Inspire Pharmaceuticals (09/01/06-present)
    “A Multi-center, Double-blind, Placebo-controlled Randomized, Efficacy and Safety Study of Denufosol Tetrasodium (INS37217) Inhalation Solution in Patients with Mild Cystic Fibrosis Lung Disease”
    Role: PI for University of Wisconsin site of multicenter study
  • Cystic Fibrosis Foundation (7/1/07-6/30/08)
    Role: Primary Sponsor, First Year Clinical Fellowship Grant for Benjamin Tippets, MD
  • Cystic Fibrosis Foundation (7/1/07-6/30/08)
    Role: Director, Cystic Fibrosis Center, University of Wisconsin
  • State of Wisconsin (7/1/07-6/30/08)
    “2008 Congenital Disorders Program: Cystic Fibrosis Newborn Screening”
    Role: PI
  • Cystic Fibrosis Foundation (12/1/07-11/30/08)
    “Clinical Research Facilitation Award”
    Role: PI
  • Cystic Fibrosis Foundation (7/1/08-6/30/09)
    Role: Primary Sponsor, First Year Clinical Fellowship Grant for Benjamin Tippets, MD
  • State of Wisconsin (7/1/08-6/30/09)
    “2008 Congenital Disorders Program: Cystic Fibrosis Newborn Screening”
    Role: PI
  • Cystic Fibrosis Foundation (7/1/08-6/30/09)
    Role: Director Cystic Fibrosis Center, University of Wisconsin

Theresa W. Guilbert, MD

  • UW Institute for Clinical and Translational Research Type I Research Pilot Program Grant (7/01/08-6/30/09)
    “Innate Immune Response to RSV in Early Life”
    Role: PI
  • NIH/NHLBI U10 HL64305 (9/30/04-8/31/09)
    “Childhood Asthma: Initiation and Intervention”
    This collaborative pediatric asthma research network encourages and facilitates advancement in the diagnosis, pathogenesis, and treatment of children and adolescents with asthma.
    Role: Co-investigator
  • NIH/NHLBI 2 P01 HL070831-06A1 (03/01/08–02/28/13)
    “COAST III Application–Rhinovirus Infection and Childhood Asthma”
    Role: Co-investigator
  • NIH/NHLBI K08 HL071742-01 (7/01/03-6/30/08)
    “Innate Immunity and RSV Infection in Children”
    Role: PI

Mary K. Schroth, MD

  • Wisconsin Integrated Systems for Communities Initiative (WISC-I) (5/01/07-4/30/08)
    Contribute to the implementation of the “Wisconsin Transition Medical Home Learning Collaborative,” which transitions youth with special health care needs to adult health care systems in a tertiary care setting.