Division Highlights - Cardiology

2007 - 2008 Highlights

Division with the most outreach clinics

Carter Ralphe, MD, and Erin Marriott, NP, join division

Kathleen Maginot, MD, develops pediatric pacemaker clinic and collaborative interventional electrophysiology clinic with the University of Iowa

John Hokanson, MD, developed collaborative catheter program with University of Kentucky

Shardha Srinivasan, MD, develops embryology training CD for echocardiography technicians


The Division of Pediatric Cardiology’s ultimate goal is to improve the cardiovascular health of children. Our coordinated team approach to care relies on contributions from—and clear communication with—pediatric specialty physicians, nurses, technicians, patients, families, and referring physicians.

We participate in several hospital-based multidisciplinary clinics, staff an extensive network of outreach clinics, and interpret echocardiograms from hospitals in the outreach network.

Special interests include cardiac imaging (including magnetic resonance imaging and fetal echocardiography), exercise physiology, interventional catheterization, and adult congenital heart disease.

We also provide outstanding education to medical students, residents, and clinicians throughout Wisconsin and surrounding areas.

Our research investigates how the developing heart responds energetically to the stress of congenital heart disease or other contractile abnormalities.


Division Chief: J. Carter Ralphe, MD, Assistant Professor John S. Hokanson, MD, Associate Professor

J. Carter Ralphe, MD


Residency: University of Iowa Hospitals and Clinics

Fellowships: University of Iowa Hospitals and Clinics

Board certification: Pediatrics, Pediatric Cardiology

Clinical interests: complex congenital heart defects, cardiomyopathy, and novel diagnostic tools and treatment of pediatric heart failure

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John S. Hokanson, MD

Residency: University of Wisconsin Hospitals and Clinics

Fellowships: Pediatric Cardiology, University of Minnesota

Board certification: Pediatrics, Pediatric Cardiology

Clinical interests: cardiac catheterization and the care of adults with congenital heart disease

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Kathleen R. Maginot, MD, Associate Professor Shardha Srinivasan, MD, Assistant Professor

Kathleen R. Maginot, MD

Residency: Children’s Hospital Medical Center, University of Cincinnati, OH

Fellowships: Pediatric Cardiology at UCLA Center for Health Services Pediatric Electrophysiology and Pacing (EP) at UCLA Children's Hospital

Board certification: Pediatrics, Pediatric Cardiology

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Shardha Srinivasan, MD

Residency: Montifi ore Medical Center/Albert Einstein College of Medicine, NY

Fellowships: Pediatric Cardiology, New York University Medical Center, NY; Cardiac Imaging, Children’s Hospital in Boston, MA

Board certification: Pediatrics, Pediatric Cardiology

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Allen D. Wilson, MD, Professor  

Allen D. Wilson, MD

Residency: Riley Children’s Hospital/ Indiana University

Fellowships: Pediatric Cardiology, Children’s Memorial Hospital, Chicago, IL and Children’s Medical Center Cincinnati, OH

Board certification: Pediatrics, Pediatric Rheumatology

Clinical interests:fetal and neonatal echocardiography and Kawasaki’s disease

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Recent Publications

J. Carter Ralphe, MD

Mamoi N, Tinney JP, Liu LJ, Elshershari H, Hoffman PJ, Ralphe JC, Keller BB, Tobita K. 2008. Modest maternal caffeine exposure affects developing embryonic cardiovascular function. Am J Physiol Heart Circ Physiol. 2008 May; 294(5): H2248-H2256. PubMed PMID: 18359892

John S. Hokanson, MD

Lovering AT, Strickland MK, Amann M, Murphy JC, O’Brien MJ, Hokanson JS, Eldridge MW. Hyperoxia prevents exercise-induced intrapulmonary arteriovenous shunt in healthy humans. J Physiology. 2008 Aug 7. PubMed PMID: 18687713

Lovering AT, Romer LM, Haverkamp HC, Pegelow DF, Hokanson JS, Eldridge MW. Intrapulmonary shunting and pulmonary gas exchange during normoxic and hypoxic exercise in healthy humans. J Appl Physiol. 2008; 104(5): 1418-1425. PubMed PMID: 18292301

Hokanson JS, Gimelli G, Bass JL. Percutaneous Closure of a large PDA in a 35-year-old man with elevated pulmonary vascular resistance. Congenital Heart Disease. 2008 Mar 3. 3(2):149-154. PubMed PMID: 18380767

Lovering AT, Romer LM, Haverkamp HC, Hokanson JS, Eldridge MW. Excessive gas exchange impairment during exercise in a subject with a history of bronchopulmonary dysplasia and high altitude pulmonary edema. High Alt Med Biol. 2007; 8(1):62-67. PubMed PMID: 17394419

Kathleen R. Maginot, MD

Maginot K, Srinivasan S, Hokanson J, De’Oliveira N, Bednarz J, Wilson AD. Right ventricular myxoma in an asymptomatic adolescent with a history of Ewing’s sarcoma. Clin Cardiol. 2009 Jul. 32(7): E32. PubMed PMID: 19382277

Rice G, Brazelton T 3rd, Maginot K, Srinivasan S, Hollman G, Wolff JA. Medium chanin acyl-coenzyme A dehydrogenase deficiency in a neonate. N Engl J Med. 2007 Oct 25. 357(17): 1781. PubMed PMID: 17960024

Ng B and Maginot KR. Sudden cardiac death in young athletes: trying to find the needle in the haystack. WMJ. 2007 Sept; 106(6):335-342. PubMed PMID: 17970016

Shardha Srinivasan, MD

Rice G, Brazelton T 3rd, Maginot K, Srinivasan S, Hollman G, Wolff JA: Medium chain acyl-coenzyme A dehydrogenase deficiency in a neonate. N Engl J Med. 2007 Oct 25. 357(17): 1781. PubMed PMID: 17960024

Srinivasan S, Strasburger J. Overview of fetal arrhythmias. Curr Opin Pediatr. 2008 Oct. 20(5):522-31. PubMed PMID: 18781114

Grant Support

J. Carter Ralphe, MD

  • NIH/NHLBI K08 HL074224-01 (04/05-05/10)
    “Expression and Function of EAATs in the Heart”
    Characterizes the role of the EAAT family of glutamate transporters in the heart.
    Role: PI
  • AHA BGIA 0765303U (07/07-06/09)
    “Mitochondrial Maturation and Function in the Engineered Heart Model”
    Established the phenotype of neonatal rat cardiomyocytes grown in a 3D culture environment compared to intact immature myocardium..
    Role: PI