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Representative Publications

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Barfield RC, Otto M, Houston J, Holladay M, Geiger T, Martin J, Leimig T, Gordon P, Chen X, R.  A one-step large-scale method for T- and B-cell depletion of mobilized PBSC for allogeneic transplantation.  Cytotherapy 6:1-6, 2004. PMID: 14985161.

Chen X, Barfield RC, Benaim H, Leung W, Knowles J, Lawrence D, Otto M, Shurtleff SA, Neale GA, Behm FG, Turner V, Handgretinger R.  Prediction of T-cell reconstitution by assessment of T-cell receptor excision circle before allogeneic hematopoietic stem cell transplantation in pediatric patients.  Blood 105:886-893, 2004. PMID: 15358630.

Otto M, Barfield RC, Iyengar R, Gatewood J, Muller I, Holladay MS, Houston J, Leung W, Handgretinger R.  Human gamma delta T cells from G-CSF-mobilized donors retain strong tumoricidal activity and produce immunomodulatory cytokines after clinical-scale isolation.  J Immunother 28:73-78, 2005. PMID: 15614047.

Otto M, Barfield RC, Martin WJ, Iyengar R, Leung W, Leimig T, Chaleff S, Gillies SD, Handgretinger R. Combination immunotherapy with clinical-scale enriched human γδ T cells, hu14.18 antibody and the immunocytokine Fc-IL7 in disseminated neuroblastoma. Clin Cancer Res 11:8486-8491, 2005. PMID: 16322312.

Otto M, Chen X, Martin WJ, Leung W, Knowles J, Holladay MS, Houston J, Handgretinger R, Barfield RC. Selection of stem cells by using antibodies that target different CD34 epitopes yields different patterns of T cell differentiation. Stem Cells 25(2):537-42, 2007. PMID: 17023516.

Chaleff S, Otto M, Barfield RC, Leimig T, Iyengar R, Martin WJ, Holladay M, Houston J, Geiger T, Huppert V, Handgretinger R. A large-scale method for the selective depletion of αβ T-lymphocytes from PBSC for allogeneic transplantation. Cytotherapy 9(8): 746-54, 2007. PMID: 17917892.

Barfield RC, Chen X, Otto M, Handgretinger R. Beyond the FACS. Stem Cells 25(11):2972, 2007.

Sorkin LS, Otto M, Baldwin WM, Vail E, Gillies SD, Handgretinger R, Barfield RC, Yu HM, Yu AL.
Anti-GD2 with an FC point mutation reduces complement fixation and decreases antibody induced allodynia. Pain 149(1):135-142, 2010. PMID: 20171010.

Jiao P, Zhou H, Otto M, Mu Q, Li L, Su G, Zhang Y, Butch ER, Snyder SE, Jiang G, Yan B. Leading Neuroblastoma Cells To Die by Multiple Premeditated Attacks from a Multifunctionalized  Nanoconstruct. J Am Chem Soc 133 (35): 13918-21, 2011. PMID: 21827210.

Otto M, Shulkin BL, Kundu M, Sandlund JT, Snyder SE, Metzger ML. Histiocyte-Rich Xanthomatous Pseudotumor Mimicking Relapse on Positron Emission Tomography Imaging in an Adolescent with Primary Mediastinal Diffuse Large B-cell Lymphoma. J Pediatr Hematol Oncol. 2012 Apr;34(3):232-5. PMID: 22082744.

Baiu DC, Brazel CS, Bao Y, Otto M.: Interactions of Iron Oxide Nanoparticles with the Immune System: Challenges and Opportunities for their Use in Nano-oncology. Curr Pharm Des. 2013;19(37):6606-21. PMID: 23621531.


Last updated: 03/12/2014
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