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Amy L. H. Peterson, MD

Amy L. H. Peterson, MD

Amy Peterson, MD, Awarded Wisconsin Partnership Program Funding

Posted: April 29, 2016

The Wisconsin Partnership Program Partnership Education and Research Committee (PERC) recently awarded Amy Peterson, MD, an Opportunity Grant in the amount of $100,000 over two years for her project, "Improved Diagnosis of Familial Hypercholesterolemia in Children and Families through the Wisconsin Pediatric Lipid Consortium (WPLC)." The WPLC is a proposed multi-institutional collaboration of pediatric health care clinics which will prospectively monitor the diagnostic and treatment patterns of children with familial hypercholesterolemia (FH). The aims of the WPLC are to: 1) determine the current statewide patterns for diagnosis and treatment of pediatric FH through development of a statewide database, 2) measure the impact of the diagnosis of FH in children on the identification of additional at-risk family members with FH, and 3) develop educational tools to aid pediatric health care providers in screening, diagnosis, and treatment of FH in children.


Dan G. Smelter

Dan G. Smelter

Ralphe Lab Researcher Dan Smelter Receives NIH Predoctoral Fellowship

Posted: April 29, 2016

Congratulations to Dan Smelter, predoctoral student in the lab of J. Carter Ralphe, MD, on funding of his Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (F31) from the National Institutes of Health, National Heart, Lung, and Blood Institute (NIH-NHLBI). This 3-year, pre-doctoral fellowship, in the amount of $91,677, is under the sponsorship of Dr. Carter Ralphe. In his project, "The role of the C3 domain of myosin binding protein-C in the pathogenesis of hypertrophic cardiomyopathy," the goal is to determine the effect of two highly prevalent and pathogenic mutations in a contractile protein of the heart, cardiac myosin binding protein-C, and how they lead to disease. The objective of understanding the underlying disease mechanism is to discover new treatment approaches that can prevent the development of the disease.


Nathan W. York

Nathan W. York

Pillers-Pattnaik Lab Graduate Student Receives Travel Award

Posted: April 29, 2016

Nathan York, graduate student and research assistant in the lab of De-Ann Pillers, MD, PhD, and Bikash Pattnaik, PhD, recently received a travel award sponsored by the National Institutes of Health/National Eye Institute (NIH-NEI). This competitive award was received for a high score on his submitted abstract, and the research findings in the abstract were considered to be of high interest to the vision and ophthalmology research community. The funds awarded will allow him to travel to the Association for Research in Vision and Ophthalmology (ARVO) annual meeting May 1-5, 2016, in Seattle, WA. Congratulations, Nathan!


Nine Students and Mentors Chosen by the Shapiro Summer Research Program

Posted: April 26, 2016

The following nine students and their mentors were recently awarded Shapiro Summer Research Awards. The Shapiro Summer Research Program provides opportunities for first-year medical students to participate in eight- to 12-week summer research projects with UW-Madison faculty members. First-year medical students apply at the beginning of each calendar year with basic science, clinical, translational, public health, or health systems projects. Funding for the program comes from the Herman and Gwendolyn Shapiro Foundation, with additional support from SMPH departments, centers and investigator grants. Congratulations to the following faculty and students:

  • Christian Capitini, MD and Krishanu Saha, PhD - student, Brady Olson. "Tagging CAR T Cells Targeting GD2+ Pediatric Neuroblastoma Using CRISPR Cas9"
  • Ryan Coller, MD, MPH and Mary Ehlenbach, MD - student, Evan Goyette. "Are Hospitalizations Among Children with Medical Complexity Sensitive to Ambulatory Care?"
  • James Conway, MD - student, Jessica Chung. "Evaluating the Effects of Ethnicity and Legal Status on Childhood Vaccinations in Chiang Mai Province, Thailand"
  • James Conway, MD and Nasia Safdar, MD, PhD - student, Youhi Ghouse. "An Investigation on Factors that Influence the Antibiotic Prescribing Habits of Alternative Providers and Seeking Habits of Villagers in Rural India"
  • Pamela Kling, MD and Carol Diamond, MD - student, Nicholas Bohrer. "Baseline Hemoglobin - Inheritance and Environment"
  • Megan Neuman, MD and Lawrence Hanrahan, PhD - student, Rachel Rongstad. "Predictors of Food Insecurity"
  • Bikash Pattnaik, PhD, MD - student, Samuel Bauer. "Kir7.1 Novel LCA16 Mutation and its Pathophysiology"
  • Amy Peterson, MD - student, Amy Zawacki. "Correlation Between Lipoprotein(a) Levels and Age of Onset of Cardiovascular Disease in Family Members of a Pediatric Familial Hypercholesterolemia Population"
  • Paul Sondel, MD, PhD - student, Claire Baniel. "The Effects of Local Radiation and Immunocytokine on Antibody Quality and Diversity"
Christian M. Capitini, MD

Christian M. Capitini, MD

Ryan J. Coller, MD, MPH

Ryan J. Coller, MD, MPH

James H. Conway, MD

James H. Conway, MD

Carol A. Diamond, MD

Carol A. Diamond, MD

Mary L. Ehlenbach, MD

Mary L. Ehlenbach, MD

Pamela J. Kling, MD

Pamela J. Kling, MD

Megan F. Neuman, MD

Megan F. Neuman, MD

Bikash R. Pattnaik, PhD

Bikash R. Pattnaik, PhD

Amy L. H. Peterson, MD

Amy L. H. Peterson, MD

Paul M. Sondel, MD, PhD

Paul M. Sondel, MD, PhD

   

Jennifer Laffin, PhD

Jennifer Laffin, PhD

Jennifer Laffin, PhD, FACMG, Is New Clinical Laboratory Genetics Fellowship Program Director

Posted: March 22, 2016

Jennifer Laffin, PhD, FACMG is the new director of the Department of Pediatrics’ Genetics & Metabolism clinical laboratory fellowship program. The program comprises three fellowship opportunities -- biochemical genetics, clinical cytogenetics and molecular genetics – all of which are accredited by the American Board of Medical Genetics and Genomics (ABMGG).

It’s one of only 45 ABMGG-accredited programs nationwide, and one of only 25 to offer training in all three genetics subspecialties. These programs provide a valuable educational opportunity for postdoctoral learners interested in the growing fields of medical genetics and genomics, and precision/personalized medicine.


Myriam Bouchlaka, PhD

Myriam Bouchlaka, PhD

Christian Capitini, MD

Christian Capitini, MD

UW Research Team Moves Cancer Immunotherapy Another Step Ahead

Posted: March 14, 2016

Myriam N. Bouchlaka, PhD, and Christian Capitini, MD, are authors on a new study that provides a key step in monitoring if, and how, the body's own cancer-killing components are working during immunotherapy.

So-called natural killer (NK) cell cancer therapy is the subject of several recent and current clinical trials, with some, but not all, patients' tumors shrinking in response to the treatment.

In the study, published in the journal OncoImmunology, the research team combined NK cell immunotherapy with the labeling agent fluorine-19 in an attempt to monitor the cancer-killing cells in an animal model that could be safely translated to humans.

They showed that the labeling had no detrimental effects on the ability of those cells to kill cancer cells in the lab. They then injected labeled cells directly into mice harboring human cancers and, using a specialized MRI to detect fluorine-19, were able to detect the labeled cells for several days in those tumors.

Read more


Steven Koslov, MD

Steven Koslov, MD

Steven Koslov, MD, is Lead Author on Primary Care Transformation Study

Posted: March 8, 2016

A research team at the University of Wisconsin School of Medicine and Public Health discovered that an overhaul of the UW Health primary care system resulted in increased patient satisfaction, improved clinical safety metrics and publicly reported preventive-care outcomes.

The Department of Pediatrics' Steven Koslov, MD, was the lead author of the study, which was published in the Journal of Delivery Science and Innovation.

The researchers reviewed the process of UW Health’s primary care transformation, which included family medicine and community health, general pediatrics and adolescent medicine and internal medicine. The goal of the redesign was to achieve the “triple aim” of better patient care, improved population health and reduced costs.

The study suggests that the UW Health experience could be useful for other academic health centers planning to redesign primary care.

Study authors are members of the UW Health Primary Care Academics Transforming Healthcare (PATH) collaborative, a multidisciplinary coalition of physicians and change leaders who aim to bridge primary care clinical transformation and rigorous scientific study in order to improve our health system for the benefit of patients and communities.

Read more


Bruce Klein

Bruce Klein, MD

Bruce Klein's Research Reveals How Fungi Hijack the Body's Immune System

Posted: March 1, 2016

Research led by Bruce Klein, MD, has uncovered a clever way fungi can hijack the body’s attempts to clear a fungal infection. Enzymes produced by the fungus mimic cell signals that temper white blood-cell development, normally used by the body to manage inflammatory responses.

In a recent study published in the journal Cell Host & Microbe, researchers were able to render this fungal strategy ineffective with a treatment of sitagliptin, a pharmaceutical enzyme inhibitor approved for treatment of type 2 diabetes.

While this research was conducted in vitro and in a mouse model, Dr. Klein and collaborators want to learn if this enzyme is present in human fungal infections as well. If so, this research could lead to a valuable weapon to fight such infections.

Fungal infections arise in people with compromised immune systems, organ or stem-cell recipients, cancer patients and those on medication that weakens the immune system. However, most fungal infections actually occur in previously healthy individuals that breathe in mold spores from the soil.

Read the full story


John Frohna, MD, MPH

John Frohna, MD, MPH

John Frohna, MD, MPH To Receive MPPDA Leadership Award

Posted: March 1, 2016

Congratulations to John Frohna, MD, MPH, who has been chosen to receive the 2016 Medicine-Pediatrics Program Directors Associate (MPPDA) Leadership Award. The MPPDA Leadership in Med-Peds Award is a new award given to a physician who has made significant contribution to Medicine-Pediatrics (Med-Peds) as a profession. In selecting a recipient, predominant attention is given to a candidate who is outstanding in their clinical field, a national leader in med-peds, and has made a significant contribution to the education of med-peds residents, promoted student interest in training in med-peds, supported faculty development of med-peds, and supported the development and betterment of med-peds as a discipline. The candidate is not required to be a current member of MPPDA. The award is presented each spring at the MPPDA Meeting.


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Last updated: 03/25/2016
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